An allosteric transcription regulator called HisP regulates the enzymes for histidine biosynthesis in thebactrium Ecolis histidine modulates HisP

An allosteric transcription regulator called HisP regulates the enzymes for histidine biosynthesis in thebactrium Ecolis histidine modulates HisP activity, on binding histidine , HisP alters its conformation, markedly changing its affinityfor the regulatory sequences in the promoters of the genes for the histidine biosynthetic enzymes.A if His P function as a gne repressor ,would you expect that his P would bind more tigthly or less tigthly to the regulatory esquence when histidine is abundant? explain your answerB if His P fucnction as a gene activator, would you expect that HisP would bind more tightly or less tightly to the regulatory sequences when histidine levels are low ? expalin your answer

 

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